Gastic Pro-Kinetic Agents
Slow clearance of food (slow gastric emptying) is a very common condition associated with anorexia, diabetic/uremic gastroparesis, old age, post-surgery and at high altitude, leading to weight loss. The conventional treatments are prolonged, costly, and probably ineffective in many situations. DRDO has developed several cost-effective formulations based on the novel concept of local gastric pro-kinator action. Hitherto unsuspected local pro-kinator action of a few safe drug molecules was discovered by scintigraphy in human subjects. Not only are the formulations safe for prolonged human use, their action is almost instantaneous and potent, enhancing the gastric emptying by up to 500 per cent. Multicentric trials are now in progress in collaboration with Maulana Azad Medical College and Jamia Hamdard.
Dynamic radioactive food study shows
normal gastric emptying till 18th min when DRDO formulation was given. A big
Formulations for Biliary Colic & Congestion